Poly-dopamine-Beta-Cyclodextrin Modified Glassy Carbon Electrode as a Sensor for the Voltammetric Detection of L-Tryptophan at Physiological pH

The main purpose of this report was to develop application of poly-dopamine-beta-cyclodextrin modifi ed glassy carbon electrode (PDA-β-CD-GCE) towards electrooxidation and determination of L-Tryptophan (L-Trp) and also the evaluation its kinetic parameters. In continuation of our efforts to use PDA-β-CD-GCE for amino acids detection, our objective in the present work was to expand application of this sensor for the determination of L-Trp which is very sensitive. Research Article Poly-dopamine-Beta-Cyclodextrin Modifi ed Glassy Carbon Electrode as a Sensor for the Voltammetric Detection of L-Tryptophan at Physiological pH Mohammad Hasanzadeh1,2*, Nasrin Shadjou3,4, Sattar Sadeghi5, Ahad Mokhtarzadeh5,6 and Ayub karimzadeh5 1Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz 51664, Iran 2Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran 3Department of Nanochemistry, Nano Technology Research Center, Urmia University, Urmia 57154, Iran 4Department of Nano Technology, Faculty of Science, Urmia University, Urmia 57154, Iran 5Department of Biochemistry, Higher Education Institute of Rab-Rashid, Tabriz, Iran 6School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran *Address for Correspondence: Mohammad Hasanzadeh, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz 51664, Iran, Tel: +98(41)-33363311; Fax: +98(41)33363231; Email: mhmmd_ [email protected]; hasanzadehm@ tbzmed.ac.ir Submitted: 16 December 2016 Approved: 06 January 2017 Published: 09 January 2017 Copyright: 2017 Hasanzadeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.